Melanotan-2 (5mg) – Aussie Peptides
🧪 Potent melanocortin receptor agonist for pigmentation research.
$75.00 AUD
Product Overview
Melanotan-2 is a synthetic analog of alpha-melanocyte stimulating hormone (α-MSH) that functions as a potent agonist of melanocortin receptors. This cyclic heptapeptide has become an important research tool for investigating pigmentation pathways, UV protection mechanisms, and melanocortin receptor function.
Each vial contains 5mg of high-purity lyophilized Melanotan-2, produced under strict quality control conditions for research applications.
Specifications
Research Background
Melanotan-2 has been extensively investigated in scientific research for its potent activation of melanocortin receptors. The following research highlights are derived from published scientific literature and provided for informational purposes only:
Melanocortin Receptor Activation
Research has demonstrated Melanotan-2's high affinity for multiple melanocortin receptor subtypes (MC1R, MC3R, MC4R, MC5R), with particularly strong activity at MC1R and MC4R. This receptor profile makes it valuable for investigating differential melanocortin signaling pathways.
Source: Journal of Medicinal Chemistry, 2020
Pigmentation Research
Studies have documented significant melanin production in melanocyte cell cultures exposed to Melanotan-2, even without UV stimulation. This effect appears to involve upregulation of tyrosinase activity and enhanced melanosome transfer, providing models for studying UV-independent pigmentation mechanisms.
Source: Pigment Cell & Melanoma Research, 2021
UV Protection Mechanisms
Research models have shown enhanced photoprotection in skin cells pre-treated with Melanotan-2 before UV exposure, with reductions in DNA photoproducts and oxidative stress markers. These findings suggest applications in UV-damage protection research.
Source: Journal of Investigative Dermatology, 2022
Suggested Research Application
Melanotan-2 may be reconstituted with sterile water or appropriate buffer solutions under aseptic laboratory conditions. Due to its potent receptor affinity, research typically utilizes nanomolar to low micromolar concentration ranges depending on the experimental model.
For optimal stability, store lyophilized peptide at -20°C and protect from light and moisture. Once reconstituted, store at 2-8°C and use within 7-14 days for maximum potency. Avoid repeated freeze-thaw cycles which may compromise peptide integrity.
Important Notice
This product is NOT a therapeutic good as defined by the Therapeutic Goods Act 1989. It is not intended for human use or ingestion. For laboratory, educational, and scientific research purposes only. Use in animals or humans is strictly prohibited unless explicitly approved by a relevant authority.
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